omicverse.single.run_liana

omicverse.single.run_liana(adata, *, groupby, method='rank_aggregate', key_added='liana_res', inplace=True, **kwargs)

Run LIANA ligand-receptor inference on an AnnData object.

参数:

• adata – AnnData object used by LIANA.

• groupby (str) – Observation column with cell-type labels.

• method (str (default: 'rank_aggregate')) – LIANA method name under liana.mt. Defaults to 'rank_aggregate'.

• key_added (str (default: 'liana_res')) – Key used to store LIANA results in adata.uns when inplace=True.

• inplace (bool (default: True)) – Whether to write results back to adata.uns.

• **kwargs – Forwarded to the selected LIANA method.

返回:

LIANA result table when inplace=False; otherwise returns adata.

返回类型:

pandas.DataFrame or AnnData