omicverse.single.AnnotationRef

class omicverse.single.AnnotationRef(adata_query, adata_ref, celltype_key='celltype')

Reference-based label transfer helper for single-cell annotation.

参数:

• adata_query (AnnData) – Query AnnData that needs cell-type annotation.

• adata_ref (AnnData) – Reference AnnData with known cell-type labels.

• celltype_key (str) – Column name in adata_ref.obs containing reference cell-type labels.

返回:

Initializes concatenated query/reference data and checks feature overlap.

返回类型:

None

__init__(adata_query, adata_ref, celltype_key='celltype')

Methods

__init__(adata_query, adata_ref[, celltype_key])
predict([method, n_neighbors, pred_key, ...])	Transfer reference labels to query cells using weighted kNN.
preprocess([mode, n_HVGs, batch_key])	Preprocess concatenated query/reference data for robust label transfer.
train([method])	Train/compute an integrated embedding used for reference label transfer.