omicverse.bulk.batch_correction

omicverse.bulk.batch_correction(adata, batch_key=None, key_added='batch_correction')

Perform batch effect correction using ComBat algorithm.

参数:

• adata (AnnData) – AnnData object containing expression data.

• batch_key (default: None) – Key in adata.obs containing batch information.

• key_added (str (default: 'batch_correction')) – Name for the corrected data layer. Default: ‘batch_correction’.

返回:

The function modifies adata.layers[key_added] in place with batch-corrected expression data.

返回类型:

None