omicverse.micro.DA.wilcoxon

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omicverse.micro.DA.wilcoxon#

DA.wilcoxon(group_key, group_a=None, group_b=None, rank=None, relative=True, min_prevalence=0.1)[source]#

Two-group Mann-Whitney U test per feature.

Parameters:

  • group_key (str) – Column in adata.obs holding group labels.

  • group_a (Optional[str] (default: None)) – Labels of the two groups to compare. If omitted, the first two unique values (sorted) are used.

  • group_b (Optional[str] (default: None)) – Labels of the two groups to compare. If omitted, the first two unique values (sorted) are used.

  • rank (Optional[str] (default: None)) – If given, collapse to this taxonomic rank first.

  • relative (bool (default: True)) – Test relative abundances (proportions per sample) rather than raw counts. Mann-Whitney is scale-invariant so this mostly affects the reported fold-change.

  • min_prevalence (float (default: 0.1)) – Skip features present (>0) in fewer than this fraction of samples.

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