omicverse.micro.simulate_paired

omicverse.micro.simulate_paired(n_samples=30, n_microbes=40, n_metabolites=20, n_pairs=5, effect_range=(1.0, 2.0), depth_range=(1000, 10000), seed=0)

Build a paired microbe + metabolite cohort with planted producer pairs.

Returns (adata_microbe, adata_metabolite, truth) where truth is a DataFrame with columns microbe / metabolite / effect listing the planted microbe→metabolite log-linear associations.

Parameters:

• n_samples (int (default: 30))

• n_microbes (int (default: 40))

• n_metabolites (int (default: 20))

• n_pairs (int (default: 5))

• effect_range (Tuple[float, float] (default: (1.0, 2.0)))

• depth_range (Tuple[int, int] (default: (1000, 10000)))

• seed (int (default: 0))