omicverse.micro.clr

Contents

omicverse.micro.clr#

omicverse.micro.clr(adata, layer_out='clr', copy=False)[source]#

CLR transform: log(x_i) - mean(log(x)) per sample (post pseudo-count).

Result is written to adata.layers[layer_out]. Negative values are expected; this is a vector-space transform that removes closure.

Parameters:

  • adata (AnnData)

  • layer_out (str (default: 'clr'))

  • copy (bool (default: False))

Contents